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Details for messenger / hormone: GLP-2

EndoNet ID: ENH00467

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Synonyms

  • Glucagon
  • GLP-2
  • glucagon-like peptide 2
  • GLP2

General information

  • GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [1]
  • GLP-2 is a 33-aa proglucagon-derived peptide produced by intestinal enteroendocrine cells. [1]

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • glucagon family

      Composition

      Sequence
      HADGSFSDE MNTILDNLA ARDFINWLI 
      QTKITD
      UniProt P01275

      Links to other resources

      UniProt P01275
      Ensembl ENST00000418842
      KEGG hsa:2641
      • Anatomical structure: enteroendocrine_cell_of_gastrointestinal_tract

      • Anatomical structure: nuclei_of_solitary_tract

      Targets

      Reference