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Details for messenger / hormone: nocistatin

EndoNet ID: ENH00475

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  • nocistatin
  • PNOC
  • prepronociceptin

General information

  • Negatively regulates pain response.
  • Nocistatin is a novel bioactive peptide produced from the same precursor as Noc/OFQ, and it plays important roles in the regulation of pain transmission and learning and memory processes in the central nervous system. [1]
  • Nocistatin is a peptide that blocks nociceptin action in pain transmission. [2]


Hormone function

  • CNS function
    • pain

    Chemical classification

    • hormone
      • genome-encoded
        • peptide neurotransmitters

    Links to other resources

    • Anatomical structure: brain

    • Anatomical structure: cerebrospinal_fluid


    No records found.