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Details for messenger / hormone: Wnt-7b

EndoNet ID: ENH00487

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Synonyms

  • WNT7B
  • protein Wnt-7b
  • Wnt-7b

General information

  • All Wnts contain 23-24 cysteine residues. [1]
  • Optimal Wnt signaling also requires association with glycosaminoglycans (e.g. heparin sulfate and chondroitin sulfate) in the extracellular matrix. [1]

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    • hormone
      • genome-encoded
        • Wnt family

      Composition

      Sequence 
      LGANIICNK IPGLAPRQR AICQSRPDA 
IIVIGEGAQ MGINECQYQ FRFGRWNCS 
ALGEKTVFG QELRVGSRE AAFTYAITA 
AGVAHAVTA ACSQGNLSN CGCDREKQG 
YYNQAEGWK WGGCSADVR YGIDFSRRF 
VDAREIKKN ARRLMNLHN NEAGRKVLE 
DRMQLECKC HGVSGSCTT KTCWTTLPK 
FREVGHLLK EKYNAAVQV EVVRASRLR 
QPTFLRIKQ LRSYQKPME TDLVYIEKS 
PNYCEEDAA TGSVGTQGR LCNRTSPGA 
DGCDTMCCG RGYNTHQYT KVWQCNCKF 
HWCCFVKCN TCSERTEVF TCK

      Links to other resources

      UniProt P56706
      Ensembl ENST00000339464
      KEGG hsa:7477

      • Anatomical structure: osteoblast

        • Wnt7b is produced by osteoblasts. [1]

      Targets

      Cellfrizzled 10
      adrenal medulla Present
      brain Present
      cerebellar cortex Present
      cerebellum Present
      heart Present
      hippocampus Present
      left coronary artery Present
      pancreas Present
      placenta Present
      putamen Present
      right coronary artery Present
      skeleton muscle Present
      spinal cord Present
      spleen Present
      substantia nigra Present
      Reference