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Details for messenger / hormone: sFRP-4

EndoNet ID: ENH00503

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Synonyms

  • FRPHE
  • sFRP-4
  • secreted frizzled-related protein 4
  • frizzled protein, human endometrium
  • FrpHE
  • SFRP4

General information

  • FrpHE functions as a regulator of the Wnt-frizzled signaling pathway and is involved in endometrial physiology and carcinogenesis. [1]
  • Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent. [2]

Classification

Hormone function

  • development and growth
    • embryogenesis
    • reproduction and sexual differentiation
      • reproduction

      Chemical classification

      • hormone
        • genome-encoded
          • frizzled family

        Composition

        Secreted frizzled-related protein 4

        Sequence 
        VRGAPCEAV RIPMCRHMP WNITRMPNH 
LHHSTQENA ILAIEQYEE LVDVNCSAV 
LRFFLCAMY APICTLEFL HDPIKPCKS 
VCQRARDDC EPLMKMYNH SWPESLACD 
ELPVYDRGV CISPEAIVT DLPEDVKWI 
DITPDMMVQ ERPLDVDCK RLSPDRCKC 
KKVKPTLAT YLSKNYSYV IHAKIKAVQ 
RSGCNEVTT VVDVKEIFK SSSPIPRTQ 
VPLITNSSC QCPHILPHQ DVLIMCYEW 
RSRMMLLEN CLVEKWRDQ LSKRSIQWE 
ERLQEQRRT VQDKKKTAG RTSRSNPPK 
PKGKPPAPK PASPKKNIK TRSAQKRTN 
PKRV
        UniProt Q6FHJ7

        Links to other resources

        UniProt Q6FHJ7
        Ensembl ENST00000436072
        KEGG hsa:6424

        • Anatomical structure: cell_of_endometrium_of_uterus

        Targets

        Cell
        No records found.
        Reference