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Details for messenger / hormone: sFRP-5

EndoNet ID: ENH00506

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Synonyms

  • SARP-3
  • sFRP-5
  • SFRP5
  • SARP3
  • secreted frizzled-related protein 5
  • secreted apoptosis-related protein 3
  • frizzled-related protein 1b
  • FRP-1b
  • FRP1B

General information

  • SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
  • Function as modulators of Wnt signaling by interacting directly with Wnts.

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    • hormone
      • genome-encoded
        • frizzled family

      Composition

      Secreted frizzled-related protein 5 chain

      Sequence 
      EEYDYYGWQ AEPLHGRSY SKPPQCLDI 
PADLPLCHT VGYKRMRLP NLLEHESLA 
EVKQQASSW LPLLAKRCH SDTQVFLCS 
LFAPVCLDR PIYPCRSLC EAVRAGCAP 
LMEAYGFPW PEMLHCHKF PLDNDLCIA 
VQFGHLPAT APPVTKICA QCEMEHSAD 
GLMEQMCSS DFVVKMRIK EIKIENGDR 
KLIGAQKKK KLLKPGPLK RKDTKRLVL 
HMKNGAGCP CPQLDSLAG SFLVMGRKV 
DGQLLLMAV YRWDKKNKE MKFAVKFMF 
SYPCSLYYP FFYGAAEPH
      UniProt Q5T4F7

      Links to other resources

      UniProt Q5T4F7
      Ensembl ENST00000266066
      KEGG hsa:6425

      • Anatomical structure: pancreas

      • Anatomical structure: retina

      • Anatomical structure: brain

      • Anatomical structure: heart

      • Anatomical structure: muscle

      • Anatomical structure: retinal_pigment_epithelium_RPE

      Targets

      Cell
      No records found.
      Reference