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Details for messenger / hormone: twisted gastrulation

EndoNet ID: ENH00510

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Synonyms

  • twisted gastrulation
  • twisted gastrulation homolog 1
  • twisted gastrulation protein homolog 1
  • TSG
  • TWSG1
  • twisted gastrulation-like protein

General information

  • Twisted gastrulation is a conserved extracellular BMP antagonist. [1]
  • TSG acts as both a BMP-4 agonist in skeletogenesis and a BMP-4 antagonist in T-cell development. [2]

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Composition

    twisted gastrulation protein mature peptide

    Sequence 
    CNKALCASD VSKCLIQEL CQCRPGEGN 
CSCCKECML CLGALWDEC CDCVGMCNP 
RNYSDTPPT SKSTVEELH EPIPSLFRA 
LTEGDTQLN WNIVSFPVA EELSHHENL 
VSFLETVNQ PHHQNVSVP SNNVHAPYS 
SDKEHMCTV VYFDDCMSI HQCKISCES 
MGASKYRWF HNACCECIG PECIDYGSK 
TVKCMNCMF

    twisted gastrulation protein chain

    Sequence 
    CNKALCASD VSKCLIQEL CQCRPGEGN 
CSCCKECML CLGALWDEC CDCVGMCNP 
RNYSDTPPT SKSTVEELH EPIPSLFRA 
LTEGDTQLN WNIVSFPVA EELSHHENL 
VSFLETVNQ PHHQNVSVP SNNVHAPYS 
SDKEHMCTV VYFDDCMSI HQCKISCES 
MGASKYRWF HNACCECIG PECIDYGSK 
TVKCMNCMF
    UniProt Q9GZX9

    Links to other resources

    UniProt Q9GZX9
    Ensembl ENST00000262120
    KEGG hsa:57045

    • Anatomical structure: brain

    • Anatomical structure: lung

    • Anatomical structure: aorta

    • Anatomical structure: testis

    Targets

    Cell
    No records found.
    Reference