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Details for messenger / hormone: gremlin-2

EndoNet ID: ENH00512

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  • CKTSF1B2
  • DAN domain family member 3
  • gremlin-2
  • cysteine knot superfamily 1, BMP antagonist 2
  • protein related to DAN and cerberus
  • DAND3
  • PRDC

General information

  • GREMLIN and DANTE are secreted antagonists for BMPs and SLITs. [1]
  • It binds and blocks the activity of BMP-2 and BMP-4. [2]
  • Antagonist of BMP.


Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Links to other resources

    UniProt Q9H772
    Ensembl ENST00000318160
    KEGG hsa:64388
    • Anatomical structure: osteoblast

    • Anatomical structure: chondrocyte

    • Anatomical structure: ovary

    • Anatomical structure: neuron


    No records found.