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Details for messenger / hormone: IHH

EndoNet ID: ENH00531

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For an hormone that would be:

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Synonyms

  • IHH
  • indian hedgehog protein
  • HHG-2

General information

  • Indian hedgehog is expressed by mature colonocytes and regulates their differentiation in vitro and in vivo. [1]
  • Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. [1]
  • Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. [2]

Classification

Hormone function

  • development and growth
    • environment adaptation

    Chemical classification

    Links to other resources

    UniProt Q14623
    Ensembl ENST00000295731
    KEGG hsa:3549
    • Anatomical structure: colon

    Targets

    CellPTC1Smo
    brain Present
    heart Present
    kidney Present
    lung Present
    mesenchyme cell Present
    Phenotypes
    • lung development
    pancreas Present
    placenta Present
    skeleton muscle Present
    Reference