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Details for messenger / hormone: Wnt-8

EndoNet ID: ENH00536

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  • Wnt-8
  • wnt 8
  • WNT8

General information

  • Member of the Wnt1 class (inducers of secondary body axis in Xenopus), which facilitates Fzd and Lrp interactions and activates the canonical Wnt/beta-catenin pathway. [1]
  • Frizzled 8c and Frizzled 9 are functional receptors for Wnt8. [2]


Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Links to other resources


      Cellfrizzled 8frizzled 9
      brain Present
      eye Present
      heart Present
      kidney Present
      pancreas Present
      skeleton muscle Present
      testis Present