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Details for messenger / hormone: APOA1(1-242)

EndoNet ID: ENH00543

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Synonyms

  • apolipoprotein A1
  • apolipoprotein A-I
  • ApoA-I(1-242)
  • apolipoprotein A-I(1-242)
  • APOA1(1-242)
  • APOA1 (1-242)

General information

  • Function: secreted by liver and small intestine, it plays a key role in the formation, metabolism and catabolism of HDL. [1]

Classification

Hormone function

  • metabolism
    • cell metabolism

    Chemical classification

    • hormone
      • genome-encoded
        • apoproteins

      Composition

      apolipoprotein A-I(1-242)

      Sequence
      DEPPQSPWD RVKDLATVY VDVLKDSGR 
      DYVSQFEGS ALGKQLNLK LLDNWDSVT 
      STFSKLREQ LGPVTQEFW DNLEKETEG 
      LRQEMSKDL EEVKAKVQP YLDDFQKKW 
      QEEMELYRQ KVEPLRAEL QEGARQKLH 
      ELQEKLSPL GEEMRDRAR AHVDALRTH 
      LAPYSDELR QRLAARLEA LKENGGARL 
      AEYHAKATE HLSTLSEKA KPALEDLRQ 
      GLLPVLESF KVSFLSALE EYTKKLNT

      Links to other resources

      UniProt P02647
      Ensembl ENST00000375323
      KEGG hsa:335
      • Anatomical structure: small_intestine

      • Anatomical structure: hepatocyte

      Targets

      CellSR-BI
      hepatocyte Present
      Reference