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Details for messenger / hormone: IL-17F

EndoNet ID: ENH00587

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Synonyms

  • Interleukin-17F
  • IL-24
  • IL-17F
  • Interleukin-17
  • Interleukin-24
  • cytokine ML-1

General information

  • IL-17F can stimulate proliferation and activation of T-cells and PBMCs and also it have the abillity to regulate cartilage matrix and turnover and inhibits angiogenesis. [1]
  • Due to their structural similarity, IL-19, IL-20, IL-22, IL-24 and IL-26 were combined with IL-10 in the so-called IL-10 family. [2]

Classification

Hormone function

  • development and growth
    • growth inhibition
    • immune response
      • activation

      Chemical classification

      • hormone
        • genome-encoded
          • cytokines
            • IL-17 family

        Composition

        Sequence 
        MTVKTLHGP AMVKYLLLS ILGLAFLSE 
AAARKIPKV GHTFFQKPE SCPPVPGGS 
MKLDIGIIN ENQRVSMSR NIESRSTSP 
WNYTVTWDP NRYPSEVVQ AQCRNLGCI 
NAQGKEDIS MNSVPIQQE TLVVRRKHQ 
GCSVSFQLE KVLVTVGCT CVTPVIHHV 
Q

        Links to other resources

        UniProt Q96PD4
        Ensembl ENST00000336123
        KEGG hsa:112744

          Targets

          CellIL-17R
          bronchi Present
          Influences
          • ↑ IL-8
          • ↑ GROalpha
          Reference