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Details for messenger / hormone: QRFP

EndoNet ID: ENH00591

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Synonyms

  • QRF-amide
  • QRFP
  • P518
  • orexigenic neuropeptide QRFP
  • 26RFa
  • pyroglutamylated arginine-phenylalanine-amide peptide
  • RF(Arg-Phe)amide family 26 amino acid peptide
  • pyroglutamylated RFamide peptide
  • neuropeptide RF-amide

General information

  • Highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus, and white matter, also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis, and thyroid. [1]
  • The novel RF-amide QRFP is implicated in food intake and aldosterone release from the adrenal cortex. [2]

Classification

Hormone function

  • homeostasis
    • further hormone secretion
    • metabolism
      • nutrient supply

      Chemical classification

      • hormone
        • genome-encoded
          • peptide neurotransmitters

      Composition

      QRF-amide

      Sequence
      QDEGSEATG FLPAAGEKT SGPLGNLAE 
      ELNGYSRKK GGFSFRF
      UniProt P83859

      Links to other resources

      UniProt P83859
      Ensembl ENST00000343079
      KEGG hsa:347148
      • Anatomical structure: brain

      • Anatomical structure: cerebellum

      • Anatomical structure: adenohypophysis

      • Anatomical structure: retina

      • Anatomical structure: colon

      • Anatomical structure: prostate

      • Anatomical structure: testis

      • Anatomical structure: thyroid_gland

      • Anatomical structure: parathyroid_gland

      • Anatomical structure: urinary_bladder

      • Anatomical structure: medulla_oblongata

      • Anatomical structure: white_matter

      • Anatomical structure: right_coronary_artery

      • Anatomical structure: left coronary artery

      Targets

      CellQRFP-R
      cell of adrenal gland zona glomerulosa Present
      Influences
      • aldosterone
      Reference