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Details for messenger / hormone: RFRP-2

EndoNet ID: ENH00597

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Synonyms

  • neuropeptide RFRP-3
  • neuropeptide RFRP-1
  • neuropeptide VF
  • FMRFamide-related peptides
  • RFRP-2
  • neuropeptide RFRP-2
  • FaRP2
  • RFamide-related peptide 2

General information

  • RFamide-related peptides are potentially involved in pain regulation through a hypothalamo-medullary projection system, and possibly via action on neuropeptide FF 2 receptors. [1]
  • FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. [2]
  • FMRFamide-related peptide.

Classification

Hormone function

  • CNS function
    • pain

    Chemical classification

    • hormone
      • genome-encoded
        • peptide neurotransmitters
          • FaRP family

      Composition

      Sequence
      SAGATANLP LRS

      Links to other resources

      UniProt Q9HCQ7
      Ensembl ENST00000222674
      KEGG hsa:64111
      • Anatomical structure: retina

      Targets

      CellNPFF-R1
      hypothalamus Present
      Influences
      • GnRH-I
      pituitary gland of diencephalon Present
      Influences
      • FSH
      • LH
      Reference