Please wait ...

Details for messenger / hormone: NPW23

EndoNet ID: ENH00601

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • preproprotein L8
  • neuropeptide W
  • NPW23
  • neuropeptide W-23
  • hL8

General information

  • NPW is produced in gastric antral G cells. [1]
  • Stimulates food intake and prolactin release. [2]
  • Implicated in regulation of body weight. [3]
  • The two forms of NPB like NPW are produced from a single precursor gene by differential proteolytic processing at two arginine residues. [4]
  • Neuropeptide W is a 30-amino-acid peptide, endogenous ligand for the G protein-coupled receptors GPR7 and GPR8. [1]


Hormone function

  • metabolism
    • nutrient supply

    Chemical classification

    • hormone
      • genome-encoded
        • peptide neurotransmitters
          • neuropeptide B/W family



      Links to other resources

      UniProt Q8N729
      Ensembl ENST00000329610
      KEGG hsa:283869
      • Anatomical structure: mucosa_of_gastric_wall

      • Anatomical structure: stomach

      • Anatomical structure: hypothalamus


      adenohypophysis Present
      amygdaloid body Present
      cerebellum Present
      frontal lobe Present
      hippocampus Present
      trachea Present