Status
Please wait ...

Details for messenger / hormone: apelin-13

EndoNet ID: ENH00613

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • APJ endogenous ligand
  • Apelin
  • apelin-13
  • APJ endogenous ligand 13

General information

  • Apelin-13 plays an important role in the regulation of behavioral, endocrine and homeostatic responses in the human central nervous system. [1]
  • Apelin-13 represses the activity of APJ as a HIV-1 coreceptor,the interaction betweenapelin-13 and the APJ receptor is critical for further investigation of apelin-APJ functions. [2]
  • Inhibits the human immunodeficiency virus type I (HIV-1) entry in cells coexpressing CD4 and APJ. [3]

Classification

Hormone function

  • CNS function
    • mood / behaviour

    Chemical classification

    • hormone
      • genome-encoded
        • apelins

      Composition

      apelin-13

      Sequence 
      QRPRLSHKG PMPF

      Links to other resources

      UniProt Q9ULZ1
      Ensembl ENST00000307484
      KEGG hsa:8862

      • Anatomical structure: frontal_lobe

      • Anatomical structure: hypothalamus

      • Anatomical structure: thalamus

      • Anatomical structure: periventricular_nucleus_of_hypothalamus

      • Anatomical structure: adipose_tissue

      Targets

      Reference