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Details for messenger / hormone: FGF-17

EndoNet ID: ENH00653

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Synonyms

  • FGF-17
  • fibroblast growth factor 17
  • FGF17
  • FGFH

General information

  • FGF17 is an autocrine prostatic epithelial growth factor and is upregulated in benign prostatic hyperplasia. [1]
  • Involved in signals induction and patterning of embryonic brain.
  • FGF-17 is a novel secreted signaling molecule in the induction and patterning of the embryonic brain. [2]

Classification

Hormone function

  • development and growth
    • growth stimulation
      • embryogenesis

      Chemical classification

      • hormone
        • genome-encoded
          • cytokines
            • heparin-binding growth factors

        Composition

        Sequence
        TQGENHPSP NFNQYVRDQ GAMTDQLSR 
        RQIREYQLY SRTSGKHVQ VTGRRISAT 
        AEDGNKFAK LIVETDTFG SRVRIKGAE 
        SEKYICMNK RGKLIGKPS GKSKDCVFT 
        EIVLENNYT AFQNARHEG WFMAFTRQG 
        RPRQASRSR QNQREAHFI KRLYQGQLP 
        FPNHAEKQK QFEFVGSAP TRRTKRTRR 
        PQPLT
        UniProt O60258-1

        Links to other resources

        UniProt O60258
        Ensembl ENST00000359441
        KEGG hsa:8822

          Targets

          CellFGFR-4
          hepatocyte Present
          Reference