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Details for messenger / hormone: BMP-11

EndoNet ID: ENH00678

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Synonyms

  • growth/differentiation factor 11
  • growth differentiation factor 11
  • bone morphogenetic protein 11
  • BMP-11
  • BMP11
  • GDF-11
  • GDF11

General information

  • BMP-11 plays a unique role in patterning both mesodermal and neural tissues. [1]
  • GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation. [2]
  • Gdf11 is a secreted signal that acts globally to specify positional identity along the anterior/posterior axis. [3]
  • GREMLIN and DANTE are secreted antagonists for BMPs and SLITs. [4]

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Links to other resources

    UniProt O95390
    Ensembl ENST00000257868
    KEGG hsa:10220

      Targets

      CellACTRIIA
      basophil gonadotroph cell of anterior pituitary FSH Present
      Influences
      • ↑ FSH
      • ↑ LH
      cell of endometrium of uterus Present
      Phenotypes
      • cell differentiation
      Reference