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Details for messenger / hormone: GDF-1

EndoNet ID: ENH00680

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Synonyms

  • embryonic growth/differentiation factor 1
  • growth differentiation factor 1
  • GDF-1
  • GDF1
  • embryonic/growth differentiation factor

General information

  • GDF-1 and Nodal converge on ALK4 in the anterior primitive streak to control the formation of organizing centers that are necessary for normal forebrain and branchial arch development. [1]
  • May be involved in mediating cell differentiation events during embryonic development.

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • TGF-beta family

      Links to other resources

      UniProt P27539
      Ensembl ENST00000247005
      KEGG hsa:2657

        Targets

        CellALK4ALK7
        adipose tissue Present
        Phenotypes
        • regulation of adipose-tissue homeostasis
        cell of endometrium of uterus Present
        Reference