Please wait ...

Details for messenger / hormone: IL-32

EndoNet ID: ENH00707

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • tumor necrosis factor alpha-inducing factor
  • natural killer cells protein 4
  • Interleukin-32
  • IL-32
  • interleukin 32
  • NK4
  • natural killer cell transcript 4
  • IL32

General information

  • There are hints that IL-32 have an important role in the antibacterial defense and in inflammation [1]
  • Limited cleavage of IL-32alpha by PR3 enhances activities of the cytokine. [2]
  • It is recently known that IL-32 synergigizes with NOD1 and NOD2 ligand and so stimulate IL-1beta and IL-6 release in a caspase-1-dependent manner. [1]
  • Interleukin 32 plays an importat role in innate and adaptive immune responses. [1]
  • IL-32, a proinflammatory cytokine with four isoforms, induces IL-1beta, TNF-alpha, IL-6, and chemokines. [2]
  • It is even known that IFN-gamma stimulates the expression of IL-32. [1]


Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines

    Links to other resources

    UniProt P24001
    Ensembl ENST00000416912
    KEGG hsa:9235
    • Anatomical structure: epithelial_cell

    • Anatomical structure: T-lymphocyte


    No records found.