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Details for messenger / hormone: thymosin beta-4

EndoNet ID: ENH00739

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Synonyms

  • Seraspenide
  • thymosin beta-4
  • T beta 4
  • Fx
  • TB4X

General information

  • Although thymosin beta-4 was originally isolated from preparations of calf thymus fraction 5, Northern blot analysis showed that the thymosin beta-4 gene was also highly expressed in B lymphocytes, macrophages, granulocytes, and T lymphocytes. [1]
  • Actin-binding protein.
  • Function: involved in angiogenesis of endothel cells of blood vessels [2]

Classification

Hormone function

  • homeostasis
    • cardiovascular control

    Chemical classification

    • hormone
      • genome-encoded
        • thymosin beta family

      Composition

      thymosin beta-4

      Sequence 
      SDKPDMAEI EKFDKSKLK KTETQEKNP 
LPSKETIEQ EKQAGES

      Links to other resources

      UniProt P62328
      Ensembl ENST00000451311
      KEGG hsa:7114

      • Anatomical structure: B-lymphocyte

      • Anatomical structure: neutrophil_granulocyte

      • Anatomical structure: macrophage

      • Anatomical structure: T-lymphocyte

      Targets

      Cell
      No records found.
      Reference