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Details for messenger / hormone: NRG1-beta3

EndoNet ID: ENH00867

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Synonyms

  • glial growth factor
  • sensory and motor neuron-derived factor
  • acetylcholine receptor-inducing activity
  • breast cancer cell differentiation factor p45
  • Heregulin
  • neu differentiation factor
  • pro-neuregulin-1, membrane-bound isoform
  • GGFHFB1
  • NRG1-beta3
  • neuregulin1-beta3

General information

  • Expressed in spinal cord and brain. [1]

Classification

Hormone function

  • development and growth
    • growth stimulation
      • growth inhibition
        • apoptosis

        Chemical classification

        • hormone
          • genome-encoded
            • cytokines
              • neuregulin-family

          Composition

          isoform 8, sequence

          Sequence
          MSERKEGRG KGKGKKKER GSGKKPESA 
          AGSQSPALP PRLKEMKSQ ESAAGSKLV 
          LRCETSSEY SSLRFKWFK NGNELNRKN 
          KPQNIKIQK KPGKSELRI NKASLADSG 
          EYMCKVISK LGNDSASAN ITIVESNEI 
          ITGMPASTE GAYVSSESP IRISVSTEG 
          ANTSSSTST STTGTSHLV KCAEKEKTF 
          CVNGGECFM VKDLSNPSR YLCKCPNEF 
          TGDRCQNYV MASFYSTST PFLSLPE

          Links to other resources

          UniProt Q02297-8
          Ensembl ENST00000287840
          KEGG hsa:3084
          • Anatomical structure: spinal_cord

          • Anatomical structure: hippocampus

          Targets

          CellErbB2ErbB3ErbB4
          No records found.
          Reference