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Details for messenger / hormone: relaxin-1

EndoNet ID: ENH00904

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Synonyms

  • RLXH1
  • prorelaxin H1
  • relaxin 1
  • RLN1 isoform 1
  • relaxin-1
  • prorelaxin H1 isoform 1
  • relaxin 1 preproprotein isoform 1

General information

  • Function: promotes remodelling of ECM. Natural suppressor of age related fibrosis. [1]

Classification

Hormone function

  • development and growth
    • environment adaptation

    Chemical classification

    • hormone
      • genome-encoded
        • insulin family

      Composition

      Relaxin B chain. (1 times)

      Sequence
      VAAKWKDDV IKLCGRELV RAQIAICGM 
      STWS
      UniProt P04808

      Relaxin A chain. (1 times)

      Sequence
      PYVALFEKC CLIGCTKRS LAKYC
      UniProt P04808

      Links to other resources

      UniProt P04808-1
      Ensembl ENST00000223862
      KEGG hsa:6013

        Targets

        Cellrelaxin receptor 2
        bone marrow Present
        brain Present
        kidney Present
        muscle Present
        peripheral blood leukocytes Present
        testis Present
        Phenotypes
        • Cryptorchidism
        thyroid gland Present
        uterus Present
        Reference