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Details for messenger / hormone: somatostatin-14

EndoNet ID: ENH00920

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Synonyms

  • somatostatin 14
  • growth hormone release-inhibiting factor
  • Somatostatin
  • somatostatin-14
  • growth hormone release-inhibiting factor 14
  • SST-14
  • SS-14

General information

  • See also somatostatin (No 124).

Classification

Hormone function

  • homeostasis
    • further hormone secretion

    Chemical classification

    • hormone
      • genome-encoded
        • somatostatin family

      Composition

      somatostatin-14

      Sequence
      AGCKNFFWK TFTSC
      UniProt P61278

      Links to other resources

      UniProt P61278
      Ensembl ENST00000287641
      KEGG hsa:6750
      • Anatomical structure: D_cell_of_gastrointestinal_tract

      Targets

      Cellsst1sst2sst3sst4sst5
      acidophil somatotroph cell of anterior pituitary Present
      Influences
      • GH
      Present
      Influences
      • GH
      alpha cell of islet of Langerhans Present
      Present
      Influences
      • glucagon
      Present
      Influences
      • glucagon
      Present
      Influences
      • glucagon
      arcuate nucleus of hypothalamus Present
      basophil thyrotroph cell of anterior pituitary Present
      Influences
      • TSH
      Present
      Influences
      • TSH
      beta cell of islet of Langerhans Present
      Influences
      • insulin
      Present
      Influences
      • insulin
      Present
      Influences
      • insulin
      Present
      Influences
      • insulin
      Present
      Influences
      • insulin
      brain Present
      Present
      Present
      Present
      Present
      D cell Present
      Influences
      • somatostatin
      Present
      Influences
      • somatostatin
      Present
      Influences
      • somatostatin
      Present
      Influences
      • somatostatin
      hippocampus Present
      kidney Present
      Present
      lung Present
      pituitary gland of diencephalon Present
      Present
      Influences
      • ACTH
      Present
      Present
      Influences
      • PRL
      • ACTH
      placenta Present
      stomach Present
      Present
      Present
      Present
      Present
      zymogenic cell of gastric gland Present
      Phenotypes
      • inhibition of pepsinogen release
      Reference