Please wait ...

Details for messenger / hormone: SLAMF1 isoform 3

EndoNet ID: ENH00952

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • SLAMF1 isoform 3
  • signaling lymphocytic activation molecule isoform 3
  • IPO-3 secreted form
  • CDw150 secreted isoform
  • soluble form of CD150 antigen
  • sSLAM
  • secreted SLAM
  • soluble SLAM
  • CDw150
  • IPO-3
  • signaling lymphocytic activation molecule

General information

  • Strongly up-regulated in DC activated through CD40, as well as in response to inflammatory stimuli, including polyinosinic polycytidylic acid and LPS. [1]
  • SLAM up-regulation appears to be a direct result of the induction of DC maturation, as inflammatory cytokines released during this process do not affect SLAM expression. [1]
  • Engagement of SLAM enhances DC production of IL-12 and IL-8, while having no effect on production of IL-10. [1]


Hormone function

  • immune response
    • activation

    Chemical classification

    Links to other resources

    UniProt Q13291
    Ensembl ENST00000302035
    KEGG hsa:6504
    • Anatomical structure: T-lymphocyte

    • Anatomical structure: dendritic_cell_in_lymphoid_tissues