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Details for messenger / hormone: intrinsic factor

EndoNet ID: ENH00953

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Synonyms

  • intrinsic factor
  • IF
  • INF
  • gastric intrinsic factor
  • GIF

General information

  • Promotes absorption of the essential vitamin cobalamin in the ileum by specific receptor-mediated endocytosis. [1]

Classification

Hormone function

  • metabolism
    • nutrient supply

    Chemical classification

    • hormone
      • genome-encoded

    Composition

    Sequence
    STQTQSSCS VPSAQEPLV NGIQVLMEN 
    SVTSSAYPN PSILIAMNL AGAYNLKAQ 
    KLLTYQLMS SDNNDLTIG QLGLTIMAL 
    TSSCRDPGD KVSILQRQM ENWAPSSPN 
    AEASAFYGP SLAILALCQ KNSEATLPI 
    AVRFAKTLL ANSSPFNVD TGAMATLAL 
    TCMYNKIPV GSEEGYRSL FGQVLKDIV 
    EKISMKIKD NGIIGDIYS TGLAMQALS 
    VTPEPSKKE WNCKKTTDM ILNEIKQGK 
    FHNPMSIAQ ILPSLKGKT YLDVPQVTC 
    SPDHEVQPT LPSNPGPGP TSASNITVI 
    YTINNQLRG VELLFNETI NVSVKSGSV 
    LLVVLEEAQ RKNPMFKFE TTMTSWGLV 
    VSSINNIAE NVNHKTYWQ FLSGVTPLN 
    EGVADYIPF NHEHITANF TQY

    Links to other resources

    UniProt P27352
    Ensembl ENST00000257248
    KEGG hsa:2694
    • Anatomical structure: oxyntic_cell_of_gastric_gland

    Targets

    Reference