Please wait ...

Details for messenger / hormone: LTB5

EndoNet ID: ENH01001

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • leukotriene B5
  • LTB5
  • 5S,12S-dihydroxy-6Z,8E,14Z,17Z-eicosapentanenoic acid
  • 5,12-DiHEPE

General information

  • synthesis of LTB5 from endogenous icosapentaenoic acid after dietary supply (a long-term enrichment of our Western nutrition with higher doses of icosapentaenoic acid may modify the contribution of leukotrienes in reactions in which these products are of pathogenetic relevance) [1]
  • involved in numerous inflammatory diseases and possesses [1]
  • less potent inflammatory effect than LTB4 [1]
  • Binding of LTB5 to human neutrophil LTB4 high affinity binding sites is lower than that of LTB4 [1]
  • All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signaling pathways [1]


Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • not genome-encoded
        • eicosanoids/fatty acid derivatives
          • leukotrienes


      Links to other resources

      LIPID MAPS LMFA03020010
      LipidBank XPR4102


        leukocyte Present