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Details for messenger / hormone: GFAP

EndoNet ID: ENH01051

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  • GFAP
  • glial fibrillary acidic protein

General information

  • Mutations in GFAP are associated with Alexander disease, a rare disorder of the central nervous system. [1]
  • Gliosis is characterized by a marked upregulation of GFAP and is seen in many neurodegenerative diseases including Alzheimer’s disease, Down syndrome, and prion disease. [2]


Hormone function

  • CNS function

Chemical classification

  • hormone
    • genome-encoded

Links to other resources

UniProt P14136
Ensembl ENST00000253408
KEGG hsa:2670
  • Anatomical structure: astrocyte


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