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Details for messenger / hormone: 2-Arachidonyl glycerol ether

EndoNet ID: ENH01081

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Synonyms

  • 2-Arachidonyl glycerol ether
  • 2-AGE
  • noladin ether
  • 2-O-((all Z)-5',8',11',14'-Eicosatetraenyl)glycerol

General information

  • NE acts as a full agonist at human CB2 receptors and thus might have important physiological functions at peripheral cannabinoid receptors.

Classification

Hormone function

Chemical classification

  • hormone
    • not genome-encoded
      • eicosanoids/fatty acid derivatives
        • prostanoids

Links to other resources

LipidBank XPR7089

    Targets

    CellCB1CB2
    adrenal gland Present
    Influences
    • ↓ CGRP1
    • ↓ acetylcholine
    • ↓ cholecystokinin
    basket cell Present
    Influences
    • ↓ GABA
    cerebellum Present
    Influences
    • ↓ GABA
    • ↓ glutamate
    cerebral cortex Present
    Influences
    • ↓ serotonin
    heart Present
    Phenotypes
    • atrial muscle contraction
    hippocampus Present
    Influences
    • ↓ GABA
    leukocyte Present
    lung Present
    pallidum Present
    peripheral nerve system element Present
    reticular part of substantia nigra Present
    Influences
    • ↓ GABA
    spinal cord Present
    urinary bladder Present
    Phenotypes
    • urination
    Reference