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Details for messenger / hormone: FAM3B-b

EndoNet ID: ENH01094

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Synonyms

  • C21orf11
  • FAM3B-b
  • cytokine-like protein 2-21
  • protein FAM3B
  • family with sequence similarity 3, member B isoform b

General information

  • FAM3B could represent a novel class of effectors involved in the destruction of the -cells and involved in the pathogenesis of type 1 diabetes. [1]

Classification

Hormone function

Chemical classification

  • hormone
    • genome-encoded
      • cytokines
        • FAM3 family

    Composition

    Isoform b

    • Canonical sequence.
    Sequence 
    ELIPDAPLS SAAYSIRSI GERPVLKAP 
VPKRQKCDH WTPCPSDTY AYRLLSGGG 
RSKYAKICF EDNLLMGEQ LGNVARGIN 
IAIVNYVTG NVTATRCFD MYEGDNSGP 
MTKFIQSAA PKSLLFMVT YDDGSTRLN 
NDAKNAIEA LGSKEIRNM KFRSSWVFI 
AAKGLELPS EIQREKINH SDAKNNRYS 
GWPAEIQIE GCIPKERS

    Links to other resources

    UniProt P58499-1
    Ensembl ENST00000357985
    KEGG hsa:54097

    • Anatomical structure: colon

    • Anatomical structure: kidney

    • Anatomical structure: prostate

    • Anatomical structure: small_intestine

    • Anatomical structure: testis

    • Anatomical structure: pancreatic_islets

      • Likely secreted by both alpha- and beta- cells. [1]

    • Anatomical structure: spermatocyte

    • Anatomical structure: Purkinje_cell

    Targets

    Cell
    No records found.
    Reference