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Details for messenger / hormone: pancreatic alpha-amylase

EndoNet ID: ENH01129

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Synonyms

  • 1,4-alpha-D-glucan glucanohydrolase
  • pancreatic alpha-amylase
  • PA

General information

  • Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in oligosaccharides and polysaccharides.
  • Belongs to the glycosyl hydrolase 13 family.

Classification

Hormone function

  • metabolism
    • cell metabolism

    Chemical classification

    • hormone

    Composition

    PA (1 times)

    • Binds 1 calcium ion per subunit. Binds 1 chloride ion per subunit.
    Sequence 
    MKFFLLLFT IGFCWAQYS PNTQQGRTS 
IVHLFEWRW VDIALECER YLAPKGFGG 
VQVSPPNEN VAIYNPFRP WWERYQPVS 
YKLCTRSGN EDEFRNMVT RCNNVGVRI 
YVDAVINHM CGNAVSAGT SSTCGSYFN 
PGSRDFPAV PYSGWDFND GKCKTGSGD 
IENYNDATQ VRDCRLTGL LDLALEKDY 
VRSKIAEYM NHLIDIGVA GFRLDASKH 
MWPGDIKAI LDKLHNLNS NWFPAGSKP 
FIYQEVIDL GGEPIKSSD YFGNGRVTE 
FKYGAKLGT VIRKWNGEK MSYLKNWGE 
GWGFVPSDR ALVFVDNHD NQRGHGAGG 
ASILTFWDA RLYKMAVGF MLAHPYGFT 
RVMSSYRWP RQFQNGNDV NDWVGPPNN 
NGVIKEVTI NPDTTCGND WVCEHRWRQ 
IRNMVIFRN VVDGQPFTN WYDNGSNQV 
AFGRGNRGF IVFNNDDWS FSLTLQTGL 
PAGTYCDVI SGDKINGNC TGIKIYVSD 
DGKAHFSIS NSAEDPFIA IHAESKL
    UniProt P04746
    KEGG hsa:279

    Links to other resources

    UniProt P04746
    Ensembl ENST00000414303
    KEGG hsa:279

    • Anatomical structure: pancreas

      Influenced by:

      • CCK-1
        in pancreas
        • Binding of CCk to CCK-A receptors stimulates amylase release from the pancreas.

    Targets

    Cell
    No records found.
    Reference