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Details for messenger / hormone: Ephrin-B2

EndoNet ID: ENH01151

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Synonyms

  • HTK ligand
  • EPH-related receptor tyrosine kinase ligand 5
  • Ephrin-B2
  • EFNB2

General information

  • Eph receptors and their ephrin ligands comprise the largest family of receptor tyrosine kinases. [1]
  • Ephrin-B2 belongs to the ephrin-B class, which are transmembrane proteins. [1]

Classification

Hormone function

Chemical classification

  • hormone
    • genome-encoded
      • ephrin family

    Composition

    Ephrin-B2

    Sequence
    IVLEPIYWN SSNSKFLPG QGLVLYPQI 
    GDKLDIICP KVDSKTVGQ YEYYKVYMV 
    DKDQADRCT IKKENTPLL NCAKPDQDI 
    KFTIKFQEF SPNLWGLEF QKNKDYYII 
    STSNGSLEG LDNQEGGVC QTRAMKILM 
    KVGQDASSA GSTRNKDPT RRPELEAGT 
    NGRSSTTSP FVKPNPGSS TDGNSAGHS 
    GNNILGSEV ALFAGIASG CIIFIVIII 
    TLVVLLLKY RRRHRKHSP QHTTTLSLS 
    TLATPKRSG NNNGSEPSD IIIPLRTAD 
    SVFCPHYEK VSGDYGHPV YIVQEMPPQ 
    SPANIYYKV

    Links to other resources

    UniProt P52799
    Ensembl ENST00000245323
    KEGG hsa:1948

      Targets

      CellEPHB4
      placenta Present
      vascularendothelial cell Present
      Phenotypes
      • vasculogenesis
      Reference