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hypothalamic-pituitary-prolactin axis

The hypothalamic-pituitary-prolactin (HPP) axis is composed of the hypothalamus, the anterior pituitary, and the mammary glands and triggers the postpartum breast engorgement and the let-down reflex.
encluster0pituitary_gland_of_diencephaloncluster1hypothalamussec53h111Secretion PRLphen783c76lactation in mammary glandsec53h111->phen783c76bind53h153Binding PrRP20bind53h153->sec53h111bind53h122Binding TRHbind53h122->sec53h111sec361h153Secretion PrRP20sec361h122Secretion TRHsec361h153->bind53h153sec361h122->bind53h122

  • hypothalamus PrRP20 [20] [secr.]
    • PrRP20 pituitary gland of diencephalon [21] [binding] []
      • "" 1 hypothalamus PrRP20 [20] [secr.]
    • hypothalamus TRH [22] [secr.]
      • TRH pituitary gland of diencephalon [23] [binding] []
        • "" 1 hypothalamus TRH [22] [secr.]
      • pituitary gland of diencephalon PRL [24] [secr.]
        • "" 1 PrRP20 pituitary gland of diencephalon [21] [binding] []
        • "" 1 TRH pituitary gland of diencephalon [23] [binding] []
      • lactation in mammary gland [25] [phe.]
        • "" 1 pituitary gland of diencephalon PRL [24] [secr.]