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hypothalamic-pituitary-gonadal axis

The hypothalamic-pituitary-gondadal (HPG) axis involves the hypothalamus, the anterior pituitary, and the gonads and regulates the development, reproduction, and aging in males and females.
encluster0testiscluster1pituitary_gland_of_diencephaloncluster2ovarycluster3hypothalamusbind140h74Binding FSHphen677c140reproduction in testisbind140h74->phen677c140FSHbind140h38Binding LHbind140h38->phen677c140LHsec53h74Secretion FSHsec53h38Secretion LHsec53h74->bind140h74course in male organismbind97h74Binding FSHsec53h74->bind97h74course in female organismsec53h38->bind140h38LHbind97h38Binding LHsec53h38->bind97h38LHbind53h134Binding GnRH-Ibind53h134->sec53h74GnRH-Ibind53h134->sec53h38GnRH-Isec97h449Secretion estrogensec97h49Secretion progesteronephen677c97reproduction in ovarysec97h449->phen677c97estrogenphen4c97regulation of ovulation in ovarysec97h49->phen4c97progesteronephen31c76mammary gland development in mammary glandsec97h49->phen31c76progesteronephen33sexual behaviorsec97h49->phen33progesteronephen32maintainance of pregnancysec97h49->phen32progesteronebind97h74->sec97h449FSHbind97h74->sec97h49FSHbind97h38->sec97h449LHbind97h38->sec97h49LHsec361h134Secretion GnRH-Isec361h134->bind53h134GnRH-I

  • hypothalamus GnRH-I [67] [secr.]
    • GnRH-I pituitary gland of diencephalon [68] [binding] []
      • "" 1 hypothalamus GnRH-I [67] [secr.]
    • pituitary gland of diencephalon FSH [69] [secr.]
      • "" 1 GnRH-I pituitary gland of diencephalon [68] [binding] []
    • pituitary gland of diencephalon LH [70] [secr.]
      • "" 1 GnRH-I pituitary gland of diencephalon [68] [binding] []
    • FSH ovary [71] [binding] []
      • "course in female organism" 1 pituitary gland of diencephalon FSH [69] [secr.]
    • LH ovary [72] [binding] []
      • "" 1 pituitary gland of diencephalon LH [70] [secr.]
    • ovary estrogen [73] [secr.]
      • "" 1 FSH ovary [71] [binding] []
      • "" 1 LH ovary [72] [binding] []
    • reproduction in ovary [74] [phe.]
      • "" 1 ovary estrogen [73] [secr.]
    • ovary progesterone [75] [secr.]
      • "" 1 FSH ovary [71] [binding] []
      • "" 1 LH ovary [72] [binding] []
    • regulation of ovulation in ovary [76] [phe.]
      • "" 1 ovary progesterone [75] [secr.]
    • mammary gland development in mammary gland [77] [phe.]
      • "" 1 ovary progesterone [75] [secr.]
    • sexual behavior in [78] [phe.]
      • "" 1 ovary progesterone [75] [secr.]
    • maintainance of pregnancy in [79] [phe.]
      • "" 1 ovary progesterone [75] [secr.]
    • FSH testis [80] [binding] []
      • "course in male organism" 1 pituitary gland of diencephalon FSH [69] [secr.]
    • LH testis [81] [binding] []
      • "" 1 pituitary gland of diencephalon LH [70] [secr.]
    • reproduction in testis [82] [phe.]
      • "" 1 FSH testis [80] [binding] []
      • "" 1 LH testis [81] [binding] []