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calcium-vitamin D3 axis

The calcium-vitamin D3 axis occurs in the presence of low calcium blood levels and involves the parathyroid glands in addition to the kidney, the liver, and the duodenum. Main function is the making available of calcium.
encluster0livercluster1skincluster2kidneycluster3parathyroid_glandsec578h211Secretion calcidiolbind63h211Binding calcidiolsec578h211->bind63h211calcidiolbind578h58Binding vitamin D3bind578h58->sec578h211vitamin D3sec125h58Secretion vitamin D3sec125h58->bind578h58vitamin D3sec63h16Secretion calcitriolphen684c35calcium reabsorption into blood in duodenumsec63h16->phen684c35calcitriolphen551c382regulation of bone resorption in bonesec63h16->phen551c382calcitriolbind63h211->sec63h16calcidiolphen684c63calcium reabsorption into blood in kidneybind63h211->phen684c63calcidiolsec407h107Secretion PTHsec407h107->sec63h16PTHstim13sunstim13->sec125h58stim5blood calcium levelstim5->sec407h107low levels of calcium

  • skin vitamin D3 [84] [secr.]
    • "" 1 sun in [83] [sti.]
  • vitamin D3 liver [85] [binding] []
    • "" 1 skin vitamin D3 [84] [secr.]
  • liver calcidiol [86] [secr.]
    • "" 1 vitamin D3 liver [85] [binding] []
  • calcidiol kidney [87] [binding] []
    • "" 1 liver calcidiol [86] [secr.]
  • calcium reabsorption into blood in kidney [88] [phe.]
    • "" 1 calcidiol kidney [87] [binding] []
  • kidney calcitriol [89] [secr.]
    • "" 1 calcidiol kidney [87] [binding] []
    • "" 1 parathyroid gland PTH [91] [secr.]
  • parathyroid gland PTH [91] [secr.]
    • "low levels of calcium" 1 blood calcium level in [90] [sti.]
  • calcium reabsorption into blood in duodenum [92] [phe.]
    • "" 1 kidney calcitriol [89] [secr.]
  • regulation of bone resorption in bone [93] [phe.]
    • "" 1 kidney calcitriol [89] [secr.]