Details for phenotype: negative regulation of apoptosis

EndoNet ID: ENP00038

Name

negative regulation of apoptosis

This phenotype is not pathologic

GO	negative regulation of apoptosis
MeSH term	68051017

normal activity of IGF-1R
in acidophil_somatotroph_cell_of_anterior_pituitary
- Insulin-like growth factor-1 protects cells from apoptosis. [1]
normal activity of Lysophosphatidic acid receptor 1
in vascularendothelial_cell
- S1P protects VECs from serum-deprived apoptosis by nitric oxide production through S1P1 receptor. [2]
normal activity of Lysophosphatidic acid receptor 3
in vascularendothelial_cell
- S1P protects VECs from serum-deprived apoptosis by nitric oxide production through S1P3 receptor. [2]
normal activity of Vascular endothelial growth factor receptor 1
in sinusoidal_endothelial_cell
- VEGFR1 signaling is critical for endothelial cell survival. [3]
- VEGF enhances the survival of endothelial cells by regulating the activity of the anti-apoptotic Bcl-2 and inhibiting caspase-mediated cell death. [3]
normal activity of fas receptor
in lipocyte_of_liver
- CD95 ligand and other death receptor ligands act as mitogens in quiescent HSCs with simultaneous inhibition of proapoptotic signaling through an inactivating tyrosine nitration of the CD95 death receptor. [4]
normal activity of 5-HT-2B
in heart
- Serotonin via the 5-HT2B-receptor protects cardiomyocytes against serum deprivation-induced apoptosis. [5]
- 5-HT-2B signaling regulate mitochondrial function and structure thereby controlling apoptosis and myofibrillas organisation in the heart. [5]

Reference