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Statistic
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Details for phenotype: negative regulation of apoptosis
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EndoNet ID: ENP00038
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Name
negative regulation of apoptosis
General information
This phenotype is not pathologic
Links to other resources
GO
negative regulation of apoptosis
MeSH term
68051017
Phenotype triggers
normal activity of
IGF-1R
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in
acidophil_somatotroph_cell_of_anterior_pituitary
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Insulin-like growth factor-1 protects cells from apoptosis.
[1]
normal activity of
Lysophosphatidic acid receptor 1
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in
vascularendothelial_cell
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S1P protects VECs from serum-deprived apoptosis by nitric oxide production through S1P1 receptor.
[2]
normal activity of
Lysophosphatidic acid receptor 3
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in
vascularendothelial_cell
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S1P protects VECs from serum-deprived apoptosis by nitric oxide production through S1P3 receptor.
[2]
normal activity of
Vascular endothelial growth factor receptor 1
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in
sinusoidal_endothelial_cell
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VEGFR1 signaling is critical for endothelial cell survival.
[3]
VEGF enhances the survival of endothelial cells by regulating the activity of the anti-apoptotic Bcl-2 and inhibiting caspase-mediated cell death.
[3]
normal activity of
fas receptor
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in
lipocyte_of_liver
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CD95 ligand and other death receptor ligands act as mitogens in quiescent HSCs with simultaneous inhibition of proapoptotic signaling through an inactivating tyrosine nitration of the CD95 death receptor.
[4]
normal activity of
5-HT-2B
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in
heart
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Serotonin via the 5-HT2B-receptor protects cardiomyocytes against serum deprivation-induced apoptosis.
[5]
5-HT-2B signaling regulate mitochondrial function and structure thereby controlling apoptosis and myofibrillas organisation in the heart.
[5]
Reference