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Statistic
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Details for phenotype: regulation of serum calcium levels
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EndoNet ID: ENP00072
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Name
regulation of serum calcium levels
General information
This phenotype is not pathologic
Links to other resources
GO
calcium ion homeostasis
Phenotype triggers
normal activity of
CaSR
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in
thyroid_gland
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G protein-coupled extracellular calcium-sensing receptor regulates serum calcium levels by parathyroid hormone and calcitonin.
[1]
G protein-coupled extracellular calcium-sensing receptor plays central role in calcium homeostasis by recognizing and responding to small changes in extracellular calcium, modulates functions of CaSR-expressing cells as to normalize the level of extracellular calcium.
[2]
normal activity of
5-HT-2A
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in
platelet
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Agonist binding to 5-HT 2A receptor activates the IP3 second messenger system and leads to the mobilization of cytosolic calcium.
[3]
normal activity of
CaSR
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in
pancreas
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The CasR regulates the calcium concentration in the pancreatic juice by triggering ductal electrolyte and fluid secretion.
[4]
Reference
