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The information resource about the endocrine network in human.
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Statistic
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Details for phenotype: steroidogenesis
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EndoNet ID: ENP00087
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Name
steroidogenesis
General information
This phenotype is not pathologic
Links to other resources
GO
steroid biosynthetic process
Phenotype triggers
normal activity of
angiotensin II type 1 receptor
ui-button
in
ovary
ui-button
Angiotensin II has many roles in the ovary, including steroidogenesis.
[1]
normal activity of
steroidogenic factor 1
ui-button
in
gonads
ui-button
SF-1 is a master regulator of steroidogenesis whose expression is critical for normal adrenal and gonadal organogenesis. Strict maintenance of SF-1 levels is essential, and mutations causing under- or overexpression result in congenital adrenal and gonadal defects or hyperplasia, respectively
[2]
normal activity of
ER-beta
ui-button
in
Leydig_cell_of_testis
ui-button
Estrogen regulates steroidogenesis by acting through ER alpha and ER beta in the Leydig cells.
[3]
normal activity of
ER-alpha
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in
Leydig_cell_of_testis
ui-button
Estrogen regulates steroidogenesis by acting through ER alpha and ER beta in the Leydig cells.
[3]
Reference