Details for phenotype: vasoconstriction

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EndoNet ID: ENP00088

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Name

vasoconstriction

General information

This phenotype is not pathologic

Links to other resources

GO	vasoconstriction
MeSH term	68014661

Phenotype triggers

• normal activity of angiotensin II type 1 receptor ui-button
  in circulatory_system__hematopoietic_system ui-button
  • AT1 mediates vasoconstriction through Ang2 [1]
• normal activity of 5-HT-2A ui-button
  in smooth_muscle_cell ui-button
  • The 5-HT 2A receptors occur peripherally on vascular smooth muscle tissue and their function is vaso-constriction. [2]
• normal activity of Sphingosine 1-phosphate receptor 3 ui-button
  in smooth_muscle_cell ui-button
  • S1P induces the vasoconstriction of isolated canine cerebral arteries via S1P receptor 3. [3]

EndoNet at the Institut for Bioinformatics UMG Göttingen