Details for phenotype: melanin synthesis

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EndoNet ID: ENP00093

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Name

melanin synthesis

General information

This phenotype is not pathologic

Links to other resources

GO	melanin biosynthetic process

Phenotype triggers

• normal activity of MC1R ui-button
  in melanocyte ui-button
  • Alpha-MSH acts as an agonist by binding to melanocortin receptor 1 (MC1-R) and elevting intracellular cAMP to induce eumelanin synthesis in the follicular melanocytes. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen