Details for phenotype: hepatic stellate cell migration

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EndoNet ID: ENP00099

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Name

hepatic stellate cell migration

General information

This phenotype is not pathologic

Links to other resources

GO	positive regulation of cell migration

Phenotype triggers

• normal activity of CCR5 ui-button
  in lipocyte_of_liver ui-button
  • RANTES potently stimulates the migration of hepatic stellate cells due to binding to CCR5, and induces FAK phosphorylation. [1]
• normal activity of Sphingosine 1-phosphate receptor 1 ui-button
  in liver ui-button
  • S1P1 regulates migration and fibrogenic activation of HSCs. [2]
• normal activity of Sphingosine 1-phosphate receptor 3 ui-button
  in liver ui-button
  • S1P3 regulates migration and fibrogenic activation of HSCs. [2]

EndoNet at the Institut for Bioinformatics UMG Göttingen