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Statistic
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Details for phenotype: monocyte activation
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EndoNet ID: ENP00113
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Name
monocyte activation
General information
This phenotype is not pathologic
Links to other resources
GO
monocyte activation during immune response
Phenotype triggers
no activity (knock out experiment or RNAi) of
CD72
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in
B-lymphocyte
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CD100/Sema4D induces immune response through CD72, it appears to play a role in monocyte activation.
[1]
The negative regulator CD100/Sema4D regulates B cell response through shutting off CD72-mediated negative signaling.
[2]
TLR1
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in
monocyte
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We provide evidence that hBD-3 activates cells in a TLR1- and TLR2-dependent manner.
[3]
hBD-3 induces activation of monocytes and mDCs, but not pDCs or B cells, is consistent with the expected pattern of TLR2 and TLR1 expression on these cells.
[3]
TLR2
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in
monocyte
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We provide evidence that hBD-3 activates cells in a TLR1- and TLR2-dependent manner.
[3]
hBD-3 induces activation of monocytes and mDCs, but not pDCs or B cells, is consistent with the expected pattern of TLR2 and TLR1 expression on these cells.
[3]
FPRL1
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in
monocyte
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Recently, we found that a G-protein-coupled, seven-transmembrane receptor, FPRL1, mediates the migration and activation of monocytes and microglia induced by Aβ42.
[4]
Reference