Status
Please wait ...
EndoNet
The information resource about the endocrine network in human.
Search
Search a component
Browse
Browse pathways
Browse hormones
Browse hormones functions
Browse hormone classification
Browse receptors
Network
Load network
Path analysis
Process network
Help
Help
Statistic
About
Details for phenotype: macrophage activation during immune response
Top
General information
Triggers
Toolbox
Click to access the toolbox
Top
General information
Triggers
Toolbox
Click to access the toolbox
EndoNet ID: ENP00114
Add to network
Name
macrophage activation during immune response
General information
This phenotype is not pathologic
Links to other resources
GO
macrophage activation during immune response
MeSH term
68055635
Phenotype triggers
normal activity of
CD72
ui-button
in
macrophage
ui-button
CD100/Sema4D induces immune response through CD72, it appears to play a role in monocyte activation.
[1]
The negative regulator CD100/Sema4D regulates B cell response through shutting off CD72-mediated negative signaling.
[2]
normal activity of
PRLR
ui-button
in
macrophage
ui-button
It has been shown that macrophage activation and superoxide anion production responsible for killing pathogenic organisms are effects mediated by the PRLR.
[3]
Activation of macrophages was originally thought to be an action of GH. However, it has been shown that macrophage activation is an effect mediated by the prolactin receptor.
[4]
Reference
