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Details for phenotype: phosphate ion homeostasis

EndoNet ID: ENP00116

Name

phosphate ion homeostasis

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68010710

Phenotype triggers

  • normal activity of VDR
    in kidney
    • The homeostasis of serum Pi levels is effected through a complex interplay between intestinal absorption, exchange with intracellular and bone storage pools, and renal tubular reabsorption. [1]
    • These processes are primarily regulated by 1-alpha,25-dihydroxyvitamin D [1,25(OH)2D3]. [2]
  • normal activity of PTHR1
    in kidney
    • The homeostasis of serum Pi levels is effected through a complex interplay between intestinal absorption, exchange with intracellular and bone storage pools, and renal tubular reabsorption. [1]
    • These processes are primarily regulated by parathyroid hormone (PTH). [3]
Reference