Details for phenotype: acute nephrotic range proteinuria

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EndoNet ID: ENP00126

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Name

acute nephrotic range proteinuria

General information

This phenotype is not pathologic

Links to other resources

Medline Plus	003580
Disease database	25320

Phenotype triggers

• more activity (high ligand concentration, overexpression) of neuropilin 1 ui-button
  in kidney ui-button
  • Administration of recombinant Sema3a to wild-type mice induces foot process effacement and fusion, endothelial cell swelling and reversible albuminuria, representing a novel mechanism for proteinuria.

EndoNet at the Institut for Bioinformatics UMG Göttingen