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Statistic
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Details for phenotype: cell differentiation
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EndoNet ID: ENP00132
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Name
cell differentiation
General information
This phenotype is not pathologic
Links to other resources
GO
cell differentiation
MeSH term
68002454
Phenotype triggers
more activity (high ligand concentration, overexpression) of
neuropilin 1
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in
kidney
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Sema3a overexpression in podocytes during kidney organogenesis leads to abnormal podocyte differentiation with a complete absence of slit diaphragms.
[1]
Podocyte effacement might represent a final common pathway that occurs with disruption of podocyte differentiation.
[1]
normal activity of
ACTRIIA
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in
cell_of_endometrium_of_uterus
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Human endometrium expresses activin A recpetor type I and type II. Thereby, it is a target for activin A, which stimulates stromal cell differentiation along with the expression and secretion of markers of endometrial receptivity.
[2]
normal activity of
activin receptor type 2B
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in
cell_of_endometrium_of_uterus
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Human endometrium expresses activin A recpetor type I and type II. Thereby, it is a target for activin A, which stimulates stromal cell differentiation along with the expression and secretion of markers of endometrial receptivity.
[2]
Reference
