Details for phenotype: negative regulation of gene expression

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EndoNet ID: ENP00144

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Name

negative regulation of gene expression

General information

This phenotype is not pathologic

Links to other resources

GO	negative regulation of gene expression
MeSH term	68015536

Phenotype triggers

• normal activity of leptin receptor ui-button
  in adipose_tissue ui-button
  • Leptin inhibits the expression of the reate-limiting enzyme for long chain fatty acid synthesis, acetyl CoA carboxylase, in cultured adipocytes. [1]
• normal activity of TNFR1 ui-button
  in adipose_tissue ui-button
  • TNF-alpha inhibits expression of the rate-limiting enzyme for long chain fatty acid synthesis, acetyl CoA carboxylase, in cultured adipocytes. [2]

EndoNet at the Institut for Bioinformatics UMG Göttingen