Status
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Details for phenotype: dwarfism

EndoNet ID: ENP00186

Name

dwarfism

General information

This phenotype is not pathologic

Links to other resources

Medline Plus 001176
Disease database 80

Phenotype triggers

  • no activity (knock out experiment or RNAi) of growth hormone receptor
    in pituitary_gland_of_diencephalon
    • In humans, that lack GH or not have a functional GHR, dwarfism is always observed. [1]
    • Laron-like dwarfism [2]
  • no activity (knock out experiment or RNAi) of GHRH-R
    in adenohypophysis
    • dwarfism of Sindh [3]
  • no activity (knock out experiment or RNAi) of GHRH-R
    in acidophil_somatotroph_cell_of_anterior_pituitary
  • no activity (knock out experiment or RNAi) of GHRH-R
    in pituitary_gland_of_diencephalon
Reference