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Statistic
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Details for phenotype: hair growth
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EndoNet ID: ENP00189
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Name
hair growth
General information
This phenotype is not pathologic
Links to other resources
GO
positive regulation of hair follicle cell proliferation
Phenotype triggers
normal activity of
PRLR
ui-button
in
hair_follicle
ui-button
normal activity of
AR
ui-button
in
hair_follicle
ui-button
Androgens have strong effects on hair growth and appear to act through the AR on dermal papilla cells.
[1]
normal activity of
ER-alpha
ui-button
in
hair_follicle
ui-button
Estrogens appear to stimulate hair growth in man, via prolonging the anagen phase of scalp hair growth by increasing cell proliferation rates and postponing their transition to the telogen phase.
[1]
In the murine hair cycle ER alpha expression is maximal in tthe telogen follice.
[2]
normal activity of
ER-beta
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in
hair_follicle
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ER beta is strongly expressed in human scalp anagen hair follicles.
[3]
Estrogens appear to stimulate hair growth in man, via prolonging the anagen phase of scalp hair growth by increasing cell proliferation rates and postponing their transition to the telogen phase.
Reference
