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Statistic
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Details for phenotype: maturation of germ cells
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EndoNet ID: ENP00201
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Name
maturation of germ cells
General information
This phenotype is not pathologic
Links to other resources
GO
germ cell development
MeSH term
68005854
Phenotype triggers
normal activity of
PRLR
ui-button
in
testis
ui-button
Prolactin induces maturation of germ cells. Prolonged suppression of prolactin (PRL) in immature male rats inhibits the spermatocyte-spermatid conversion process, alters leydig cell morphology, decreases accessory sex organ weight and increases serum LH levels without a significant alteration in serum FSH concentration. Amelioration of these effects by exogenous PRL strongly indicates that in the absence of PRL excess titers of endogenous LH fail to exert an influence on the spermatogenic activity of maturing testes.
[1]
normal activity of
PRLR
ui-button
in
ovary
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Prolcatin induces maturation of germ cells. Prolactin appears to be an important constituent in the process of oocyte maturation, promoting preimplantation embryonic development.
[2]
Reference
